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Very possible — and the chemistry actually explains why.

4-HO-MET (metocin) is a tryptamine, but LSD and tryptamines are hitting much of the same psychedelic machinery. 4-HO-MET is closely related to psilocin (4-HO-DMT): one of psilocin's two N-methyl groups is essentially replaced by an ethyl group. Laboratory work confirms that 4-HO-MET is an agonist at 5-HT2A, the serotonin receptor most strongly associated with classic psychedelic effects. �

PubMed Central (PMC) +1

And here's the fun structural part: LSD isn't a tryptamine, but its ergoline skeleton contains an indole/amine arrangement related to the tryptamine pharmacophore. LSD also activates 5-HT2A extremely strongly. So the brain isn't going, “Ah, tryptamine — mushroom graphics please.” It's responding to overlapping receptor activation and downstream cortical circuitry.

That's why phenomena such as geometric patterning, surfaces flowing or breathing, intensified colors, tracers, repeating textures, altered depth and visual salience can occur with LSD, psilocin, 4-HO-MET, mescaline-family drugs, etc. They're different molecules taking somewhat different routes into a substantially overlapping visual-processing system.

Where LSD really separates itself is its much broader receptor pharmacology and extraordinarily high 5-HT2A affinity, plus its peculiar binding kinetics, which contribute to a qualitatively different and much longer experience. The study comparing substituted tryptamines actually measured LSD's 5-HT2A affinity at about 1.3 nM, versus substantially weaker affinity for the tryptamine compounds—yet those tryptamines still produce powerful psychedelic signaling. �

PubMed Central (PMC)

And 4-HO-MET has a reputation among users for being disproportionately visual relative to its mental/headspace effects. That's mostly anecdotal rather than something established through good controlled human trials, but its receptor pharmacology certainly doesn't make the reports mysterious.

So if someone's thought was:

“It's a tryptamine. Why the fuck am I seeing LSD-like visuals?”

The answer is basically: because “tryptamine vs. lysergamide” is a chemistry classification, not a separate graphics engine. 😆 The visual systems they're perturbing overlap considerably.

Similarity by itself also wouldn't make me suspicious that somebody had accidentally taken LSD instead of 4-HO-MET. The overlap is expected. �